| Brevilin A |
Influence on apoptosis |
Flow cytometry |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on cell cycle proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on cell cycle proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on cell cycle proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on cell cycle proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on cell cycle proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on apoptotic proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on apoptotic proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on apoptotic proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on apoptotic proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on apoptotic proteins |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
p-STAT3 |
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
STAT3 |
|
| Brevilin A |
Influence on PI3K/AKT pathway members |
Western Blot |
20.00 µM |
CNE-2 |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on tumor growth |
Average tumor volume |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
|
|
| Brevilin A |
Influence on tumor growth |
Average tumor weight |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
|
|
| Brevilin A |
Influence on tumor growth |
Average mouse body weight |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
|
|
| Brevilin A |
Influence on PI3K/AKT and STAT3 signaling pathways |
Western Blot |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
|
|
| Brevilin A |
Influence on PI3K/AKT and STAT3 signaling pathways |
Western Blot |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
|
|
| Brevilin A |
Influence on PI3K/AKT and STAT3 signaling pathways |
Western Blot |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
p-STAT3 |
|
| Brevilin A |
Influence on PI3K/AKT and STAT3 signaling pathways |
Western Blot |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
STAT3 |
|
| Brevilin A |
Influence on PI3K/AKT and STAT3 signaling pathways |
Western Blot |
20.00 mg/kg |
CNE-2 (xenograft) |
Mus musculus |
BALB/c nude |
|
|
| Brevilin A |
Influence on STAT3 signalling |
MTT |
20.00 µM |
A549R |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on STAT3 signalling |
Luciferase Assay |
20.00 µM |
A549R |
Homo sapiens |
|
|
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
20.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
20.00 µM |
HEK293T |
Homo sapiens |
|
STAT3 |
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
20.00 µM |
HEK293T |
Homo sapiens |
|
|
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
STAT3 |
|
